Chronic obstructive pulmonary disease (COPD) is a lethal progressive lung disease culminating in permanent airway obstruction and alveolar enlargement. Previous studies suggest CTL involvement in COPD
نویسندگان
چکیده
Michael T. Borchers,1,2 Scott C. Wesselkamper,1 Victor Curull,3,4,5 Alba Ramirez-Sarmiento,3,4 Albert Sánchez-Font,3,4 Judith Garcia-Aymerich,6 Carlos Coronell,3 Josep Lloreta,7,8 Alvar G. Agusti,9,10 Joaquim Gea,4,7,9 John A. Howington,11 Michael F. Reed,11 Sandra L. Starnes,11 Nathaniel L. Harris,1 Mark Vitucci,1 Bryan L. Eppert,1 Gregory T. Motz,1 Kevin Fogel,2 Dennis W. McGraw,2 Jay W. Tichelaar,12 and Mauricio Orozco-Levi3,4,7,9
منابع مشابه
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease.
Chronic obstructive pulmonary disease (COPD) is a lethal progressive lung disease culminating in permanent airway obstruction and alveolar enlargement. Previous studies suggest CTL involvement in COPD progression; however, their precise role remains unknown. Here, we investigated whether the CTL activation receptor NK cell group 2D (NKG2D) contributes to the development of COPD. Using primary m...
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